What's the best route?
Generally speaking...
Opiates + Alcohol = ok
Benzodiazepines + Opiates = ok
Opiates + Benzodiazepines + Alcohol = warning
?
I think I responded to this thread already -
but none of these three depressants should really be mixed.I would suggest putting at least three days between any sort of "fun". It makes it more worthwhile when you actually do it. I was in a relationship with a woman once. As I may have stated before, I am not a particularly sexual person. I told her that I would be willing to have sex with her once weekly, as for me once monthly is fine. Some time down there road she told me that she was more satisfied having sex with me than with her previous boyfriend because he would attempt to have sex with her on a daily basis, if not multiple times daily. She said that effectively took the fun out of it. This is true with most things.
I would say that if you are going to do opiates [I call them "free ones" because I once had a prescription, and my friend falsely thought I gave a free one to a separate friend, and then himself asked if I could give him a free one.

], put space between days. That way your receptors stay "fresh".
I do believe in there concept of receptors burnout - doesn't it make sense that the more we use *anything*, the more used/worn it gets, and the less efficiently it operates? In opiates terms, this means that if you put space between dates of consumption, you will also be "virginal" to the use, and get the full effect. Why over use something, only to spend ridiculous amounts of money to chase a smaller effect?
A friend of mine did coke and opiates, and said that the only effect was nothing - as each drug cancelled out the effects of the other.

. In other cases, certain things will potentiate a particular drug - for opiates, grapefruits are said to do that. Although individual results vary.
Another friend of mine said that he did 3x Anadrol 50 tablets, and all that happened was he got more side effects. He stated that 2x daily Anadrol 50 tablets was the sweet spot - beyond which, he sustained nothing but more sides. What's the point of that?
They say "Just say no to drugs", but I say "I want more information than that". I want my friends to enjoy their lives, and should they drink alcohol or use drugs - to do so responsibly, and get as much information as possible before proceeding. That is why threads like this are important.
Anyway, I have derailed the topic here, so let me say again what I opened this post with -
none of these three drugs should be mixed. If you are going to combine these, please do so in the company of someone you trust, and who will be able to contact medical attention, if needed. And do not state on the phone that drugs were involved. Yet another friend told me that if you call the police and state that drugs were involved, the police will show up. To me, that is awful. A drug overdose is a medical issue, not a criminal matter. It makes me wonder how many people have died by not calling 911 out of fear they would be slapped with a drug charge.
Consider that doctors have been through years of education to learn precisely how to combined opiates with benzodiazepines. So this combination is one that should be taken seriously - and more appropriately, outright avoided. But since people are going to do it anyway, I may as well tell them to do so in the company of a person [or people] who cares about safety and well-being, and who is responsible enough to contact the proper medical authorities if necessary.
Alcohol + Opiates + Benzodiazepines SHOULD NOT COMBINED UNDER ANY CIRCUMSTANCE.